Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0005p1 | Bone | BES2003

Osteoblastic gene expression in cells of the adipocytic lineage

Ioannidou-Kadis S , Staley W , Byers R , Selby P , Freemont A , Hoyland J

Osteoblasts and adipocytes are derived from the same stem cell in adult marrow and plasticity exists between the two lineages. In Osteoporosis there are reduced osteoblast numbers and increased adipocyte numbers suggesting a disturbance in the normal balance of the cells' differentiation pathways, leading to defective osteoblastogenesis and favouring adipogenesis. The stage of adipocytic differentiation at which plasticity is lost and commitment is established is not known. We...
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ea0003p3 | Bone | BES2002

Investigation into the plasticity of adult human bone marrow adipocytes

Ioannidou S , Staley W , Byers R , Selby P , Freemont A , Hoyland J

Osteoblasts and adipocytes are derived from the same stem cell in adult marrow and plasticity exists between the two lineages. In Osteoporosis there are reduced osteoblast numbers and increased adipocyte numbers suggesting a disturbance in the normal balance of the cells' differentiation pathways, leading to defective osteoblastogenesis and favouring adipogenesis. The stage of adipocytic differentiation at which plasticity is lost and commitment is established is not known. We...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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